Unnatural Amino Acids: Strategies, Designs and Applications in Medicinal Chemistry and Drug Discovery

Hydrogen-Bonding Behavior of Amidines in Helical Structure

Facile, mechanochemical functionalization of hydrophobic substrates for single walled carbon nanotube based optical reporters of hydrolase activity

Thermal Rearrangement of the S–N Bond of Thiooxime Esters

Complimentary Strategies for Installation of Thioimidates into Peptide Backbones

Thioimidates Provide General Access to Thioamide, Amidine, and Imidazolone Peptide-Bond Isosteres

General Installation of (4H)-Imidazolone cis-Amide Bioisosteres Along the Peptide Backbone

Thioimidate Solutions to Thioamide Problems during Thionopeptide Deprotection

An Anomeric Answer to Sulfenamide Stability and α-Nucleophilicity

Protein Conformational Dynamics Underlay Selective Recognition of Thermophilic over Mesophilic Enzyme I by a Substrate Analogue

A General Strategy to Install Amidine Functional Groups Along the Peptide Backbone

Attached Nitrogen Test by ¹³C–¹⁴N Solid-State NMR Spectroscopy for the Structure Determination of Heterocyclic Isomers

Hydrogen Bond and Geometry Effects of Thioamide Backbone Modifications

Investigation of a Series of 2-(2’-Hydroxyaryl)benzazole Derivatives: Photophysical Properties, Excited-State Intramolecular Proton-Transfer Reactions and Observation of Long-Lived Triplet Excited States

Molecular Conformation in Charge Tunneling across Large-Area Junctions

Magnetic shielding paints an accurate and easy-to-visualize portrait of aromaticity

Determination of Diffusion Kinetics of Ketamine in Brain Tissue: Implications for in vitro Mechanistic Studies of Drug Actions

A Decision Tree for Retrosynthetic Analysis

Surface-grafted and covalently cross-Linked polymeric ionic liquids with tunable morphology via in/ex-situ methods

Detailed visualization of aromaticity using isotropic magnetic shielding

Fast Acquisition of Proton Detected HETCOR Solid-State NMR Spectra of Quadrupolar Nuclei and Rapid Measurement of NH Bond Lengths by Frequency Selective HMQC and RESPDOR Pulse Sequences

The Malleable Excited States of Benzothiadiazole Dyes and Investigation of their Potential for Photochemical Control

Visible-light photocleavable protecting groups based on benzothiadiazole scaffolds

Controlled supramolecular complexation of cyclodextrin-functionalized polymeric ionic liquid brushes

Selective staining and quantification of intracellular lipid droplets with CBD-Fluor, a more sensitive push-pull fluorophore

Deprotection strategies for thioimidates during Fmoc solid-phase peptide synthesis: A safe route to thioamides

A bottom-up approach to preserve thioamide residue stereochemistry during Fmoc solid-phase peptide synthesis

Demonstration of Baird's rule complementarity in the singlet state and implications for excited-state intramolecular proton transfer

Synthesis and spectral properties of push-pull dyes based on isobenzofuran scaffolds

Tuning electrochemical redox potentials with boronic acid derivatives

Proton Detected ¹H-¹⁷O Double Resonance Solid-State NMR Spectroscopy

A designed protein binding-pocket to control excited-state intramolecular proton transfer fluorescence

Open resonance assisted hydrogen bonds and competing quasiaromaticity

Understanding interface (odd-even) effects in charge tunneling using polished EGaIn electrode

A small push-pull fluorophore for turn-on fluorescence

S-5-Ethynyl-anabasine, a novel compound, is a more potent agonist than other nicotine alkaloids on the nematode Asu-ACR-16 receptor