1. Thioimidates Provide General Access to Thioamide, Amidine, and Imidazolone Peptide-Bond Isosteres


    2. Byerly-Duke, J.; O'Brien, A. E.; Wall B. J.; VanVeller, B.
    Methods in Enzymology   2024, Accepted    DOI:

  2. General Installation of (4H)-Imidazolone cis-Amide Bioisosteres Along the Peptide Backbone


    3. Wall B. J.; Sharma, K. K.; O'Brien, A. E.; Donovan, A.; VanVeller, B.
    Journal of the American Chemical Society   2024, Accepted    DOI: 10.1021/jacs.3c13825

  3. Thioimidate Solutions to Thioamide Problems during Thionopeptide Deprotection


    4. Byerley-Duke, J.; VanVeller, B.
    Organic Letters   2024, 5, 1452–1457    DOI: 10.1021/acs.orglett.4c00035

  4. An Anomeric Answer to Sulfenamide Stability and α-Nucleophilicity


    5. Wall, B. J.; VanVeller, B.
    Journal of Organic Chemistry   2023, 88, 15067–15072    DOI: 10.1021/acs.joc.3c01520

  5. Protein Conformational Dynamics Underlay Selective Recognition of Thermophilic over Mesophilic Enzyme I by a Substrate Analogue


    6. Singh, A.; Burns, D.; Sedinkin, S.; VanVeller, B.; Potoyan, D.; Venditti, V.
    Biomolecules   2023, 13, 160–174   DOI: 10.3390/biom13010160

  6. A General Strategy to Install Amidine Functional Groups Along the Peptide Backbone


    7. O'Brien, E. A.; Sharma, K. K.; Byerly-Duke, J.; Camacho III, L. A.; VanVeller, B.
    Journal of the American Chemical Society   2022, 144, 22397–22402    DOI: 10.1021/jacs.2c09085
              ● Highlighted by Org. Process Res. Dev. DOI: 10.1021/acs.oprd.3c00022

  7. Attached Nitrogen Test by 13C–14N Solid-State NMR Spectroscopy for the Structure Determination of Heterocyclic Isomers


    8. Dorn, R. W.; Wall, B. J.; Ference, S. B.; Norris, S. R.; Lubach, J. W.; Rossini, A. J.; VanVeller, B.
    Organic Letters   2022, 24, 5635–5640    DOI: 10.1021/acs.orglett.2c01576
              ● Invited Front Cover
              ● Original TOC graphic rejected by journal shown below

  8. Hydrogen Bond and Geometry Effects of Thioamide Backbone Modifications


    9. Lampkin, B. J.; VanVeller, B.
    Journal of Organic Chemistry   2021, 86, 18287–18291    DOI: 10.1021/acs.joc.1c02373

  9. Investigation of a Series of 2-(2’-Hydroxyaryl)benzazole Derivatives: Photophysical Properties, Excited-State Intramolecular Proton-Transfer Reactions and Observation of Long-Lived Triplet Excited States


    10. Li, Y.; Bai, X.; Liang, R.; Zhang, X.; Nguyen, Y. H.; VanVeller, B.; Du, L.; Phillips, D. L.
    Journal of Physical Chemistry B   2021, 47, 12981–12989    DOI: 10.1021/acs.jpcb.1c05798
              ● JCP special issue to honor George Schatz

  10. Molecular Conformation in Charge Tunneling across Large-Area Junctions


    11. Du, C.; Norris, S. R.; Thakur, A.; Chen, J.; VanVeller, B.; Thuo, M.
    Journal of the American Chemical Society   2021, 143, 13878–13886    DOI: 10.1021/jacs.1c06622

  11. Magnetic shielding paints an accurate and easy-to-visualize portrait of aromaticity


    12. Karadakov, P. B.; VanVeller, B.
    Chemical Communications   2021, 57, 9504–9513    DOI: 10.1039/D1CC03701C

  12. Determination of Diffusion Kinetics of Ketamine in Brain Tissue: Implications for in vitro Mechanistic Studies of Drug Actions


    13. Geiger, Z.; VanVeller, B.; Lopez, Z.; Harrata, A. K.; Battani, K.; Points, L. J.; Yuan, L. L.
    Frontiers in Neuroscience   2021,    DOI: 10.3389/fnins.2021.678978

  13. A Decision Tree for Retrosynthetic Analysis


    14. VanVeller, B.
    Journal of Chemical Education   2021, 98, 2726–2729   DOI: 10.1021/acs.jchemed.1c00447

  14. Surface-grafted and covalently cross-Linked polymeric ionic liquids with tunable morphology via in/ex-situ methods


    15. Demirci, S.; Demirci, S. K.; VanVeller, B.
    ACS Macro Letters   2020, 9, 1806–1811   DOI: 10.1021/acsmacrolett.0c00632

  15. Detailed visualization of aromaticity using isotropic magnetic shielding


    16. Lampkin, B. J.; Karadakov, P. B.; VanVeller, B.
    Angewandte Chemie International Edition   2020, 59, 19275–19281   DOI: 10.1002/anie.202008362

              ● News highlight in Chemistry World Magazine

  16. Fast Acquisition of Proton Detected HETCOR Solid-State NMR Spectra of Quadrupolar Nuclei and Rapid Measurement of NH Bond Lengths by Frequency Selective HMQC and RESPDOR Pulse Sequences


    17. Wijesekara, A. V.; Venkatesh, A.; Lampkin, B. J.; VanVeller, B.; Lubach, J. W.; Nagapudi, K.; Hung, I.; Gor’kov, P. L.; Gan, Z.; Rossini, A. J.
    Chemistry – A European Journal   2020, 26, 7881–7888   DOI: 10.1002/chem.202000390

  17. The Malleable Excited States of Benzothiadiazole Dyes and Investigation of their Potential for Photochemical Control


    18. Warner, C. C.; Thooft, A. M.; Norris, S. R.; Lampkin, B. J.; Demirci, S. K.; VanVeller, B.
    ChemistrySelect   2020, 5, 7016–7020   DOI: 10.1002/slct.202001980

  18. Visible-light photocleavable protecting groups based on benzothiadiazole scaffolds


    19. Norris, S.; Warner, C. C.; Thooft, A. M.; Demirci, S. K.; Lampkin, B. J.; Miner, K.; Ellern A.; VanVeller, B.
    Organic Letters   2020, 22, 270–273   DOI: 10.1021/acs.orglett.9b04268

  19. Controlled supramolecular complexation of cyclodextrin-functionalized polymeric ionic liquid brushes


    20. Demirci, S.; Demirci, S. K.; VanVeller, B.
    ACS Applied Polymer Materials   2020, 2, 751–757   DOI: 10.1021/acsapm.9b01058

  20. Selective staining and quantification of intracellular lipid droplets with CBD-Fluor, a more sensitive push-pull fluorophore


    21. Suarez, S. I.; Warner, C. C.; Brown-Harding, H.; Thooft, A. M. VanVeller, B.; Lukesh, J. C. III
    Organic & Biomolecular Chemistry   2020, 18, 495-499   DOI: 10.1039/c9ob02486g
              ● High citation distinction

  21. Deprotection strategies for thioimidates during Fmoc solid-phase peptide synthesis: A safe route to thioamides


    22. Camacho III, L. A.; Nguyen, Y. H.; VanVeller, B.
    Journal of Organic Chemistry   2019, 84, 15309-15314   DOI: 10.1021/acs.joc.9b02317

  22. A bottom-up approach to preserve thioamide residue stereochemistry during Fmoc solid-phase peptide synthesis


    23. Camacho III, L. A.; Lampkin, B. J.; VanVeller, B.
    Organic Letters   2019, 21, 7015-7018   DOI: 10.1021/acs.orglett.9b02598
              ● Original TOC graphic rejected by journal shown below

  23. Demonstration of Baird's rule complementarity in the singlet state and implications for excited-state intramolecular proton transfer


    24. Lampkin, B. J.; Nguyen, Y. H.; Karadakov, P.; VanVeller, B.
    Physical Chemistry Chemical Physics   2019, 21, 11608-11614   DOI: 10.1039/C9CP02050K
              ● Hot Article Distinction

  24. Synthesis and spectral properties of push-pull dyes based on isobenzofuran scaffolds


    25. Norris, S. R.; Warner, C. C.; Lampkin, B. J.; Bouc, P. M.; VanVeller, B.
    Organic Letters  2019, 21, 3817-3821   DOI: 10.1021/acs.orglett.9b01260

  25. Tuning electrochemical redox potentials with boronic acid derivatives


    26. Robole, Z.; Rahn, K.; Lampkin, B. J.; Anand, R. K.; VanVeller, B.
    Journal of Organic Chemistry  2019, 84, 2346-2350   DOI: 10.1021/acs.joc.8b03087

  26. Proton Detected 1H-17O Double Resonance Solid-State NMR Spectroscopy


    27. Carnahan, S.; Lampkin, B. J.; Pranjali, N.; Hanrahan, M.; Slowing, I.; VanVeller, B.; Gang, W.; Rossini, A.
    Journal of the American Chemical Society   2019, 141, 441-450   DOI: 10.1021/jacs.8b10878

  27. A designed protein binding-pocket to control excited-state intramolecular proton transfer fluorescence


    28. Lampkin, B. J.; Monteiro, C.; Powers, E. T.; Bouc, P.; Kelly, J. W.; VanVeller, B.
    Organic & Biomolecular Chemistry   2019, 17, 1076-1080   DOI: 10.1039/c8ob02673d
              ● Cover Article

  28. Open resonance assisted hydrogen bonds and competing quasiaromaticity


    29. Nguyen, Y.; Lampkin, B.; Venkatesh, A.; Ellern, A.; Rossini, A.; VanVeller, B.
    Journal of Organic Chemistry   2018, 83, 9850-9857.   DOI: 10.1021/acs.joc.8b01331

  29. Understanding interface (odd-even) effects in charge tunneling using polished EGaIn electrode


    30. Chen, J.; Giroux, T.; Nguyen, Y.; Kadoma, A.; Chang, B.; VanVeller, B.; Thuo, M.
    Physical Chemistry Chemical Physics   2018, 20, 4864-4878  DOI: 10.1039/c7cp07531f

  30. A small push-pull fluorophore for turn-on fluorescence


    31. Thooft, A. M.; Cassaidy, K.; VanVeller, B.
    Journal of Organic Chemistry   2017, 82, 8842-8847.  DOI: 10.1021/acs.joc.7b00939

  31. S-5-Ethynyl-anabasine, a novel compound, is a more potent agonist than other nicotine alkaloids on the nematode Asu-ACR-16 receptor


    32. Zheng, F.; Du, X.; Robertson, A. P.; Yu, E. W.; VanVeller, B.; Martin, R. J.
    International Journal for Parasitology: Drugs and Drug Resistance  2016, 7, 12-22.  DOI: 10.1016/j.ijpddr.2016.12.001

BEFORE ISU    

  1. Target selection by natural and redesigned PUF proteins


    2. Porter, D. F.; Koh, Y. Y.; VanVeller, B.; Raines, R. T.; Wickens, M.
    Proceedings of the National Academy of Sciences, U.S.A.  2015, 112, 15868-15873.  DOI: 10.1073/pnas.1508501112

  2. Convenient synthesis of collagen-related tripeptides for segment condensation


    3. Ellison, A. J.; VanVeller, B.; Raines, R. T.
    Biopolymers  2015, 104, 674-681.  DOI: 10.1002/bip.22700

  3. Thioamides in the collagen triple helix


    4. Newberry, R. W.; VanVeller, B.; Raines, R. T.
    Chemical Communications  2015, 51, 9624-9627.  DOI: 10.1039/c5cc02685g

  4. Signatures of n→π* interactions in proteins


    5. Newberry, R. W.; Bartlett, G. J.; VanVeller, B.; Woolfson, D. N.; Raines, R. T.
    Protein Science  2014, 23, 284-288.  DOI: 10.1002/pro.2413

  5. Interplay of hydrogen bonds and n→π* interactions in proteins


    6. Bartlett, G. J.; Newberry, R. W.; VanVeller, B.; Raines, R. T.; Woolfson, D. N.
    Journal of the American Chemical Society  2013, 135, 18682-18688.  DOI: 10.1021/ja4106122

  6. Thiols and selenols as relay catalysts for disulfide-bond reduction


    7. Lukesh, J. C. III; VanVeller, B.; Raines, R. T.
    Angewendte Chemie International Edition  2013, 52, 12901-12904.  DOI: 10.1002/anie.201307481
              - Cover Article, DOI: 10.1002/anie.201309405
              - Hot Paper Distinction

  7. A divalent protecting group for benzoxaboroles


    8. VanVeller, B.; Aronoff, M. A.; Raines, R. T.
    RSC Advances  2013, 3, 21331-21334.  DOI: 10.1039/c3ra44385j

  8. A Selective detection of boronic acids through ESIPT fluorescence


    9. Aronoff, M. A.; VanVeller, B.; Raines, R. T.
    Organic Letters  2013, 15, 5382-5385.  DOI: 10.1021/ol402714k

  9. n→π* Interactions of amides and thioamides: implications for protein stability


    10. Newberry, R. W.; VanVeller, B.; Guzei, I. A.; Raines, R. T.
    Journal of the American Chemical Society  2013, 135, 7843-7846.  DOI: 10.1021/ja4033583
              - JACS Spotlight J. Am. Chem. Soc. 2013, 135, 8431.  DOI: 10.1021/ja405586p
              - Chemical & Engineering News  2012, 90 (36), 68-71.  Link: Tweeks Boost Protein Stability

  10. Synthesis and properties of triptycene-containing polyetherolefins via acyclic diene metathesis polymerization


    11. Sydlik, S. A.; Delgado, P. A.; Inomata, S.; VanVeller, B.; Yang, Y.; Swager, T. M.; Wagener, K. B.
    Journal of Polymer Science Part A: Polymer Chemistry.  2013, 51, 1695-1706.  DOI: 10.1002/pola.26557

  11. Polycyclic aromatic triptycenes: oxygen substitution cyclization strategies


    12. VanVeller, B.; Schipper, D. J.; Swager, T. M.
    Journal of the American Chemical Society  2012, 134, 7282-7285.  DOI: 10.1021/ja3018253

  12. Fluorescent amphiphiles: a novel tool for designing mild topical conference


    13. Seto, J.; Polat, B.; VanVeller, B.; Lopez, R.; Langer, R.; Blankschtein, D.
    Journal of Controlled Release  2012, 158, 85-92.  DOI: 10.1016/j.jconrel.2011.10.018

  13. Triptycene diols: a strategy for synthesizing planar π-systems


    14. VanVeller, B.; Robinson, D.; Swager, T. M.
    Angewendte Chemie International Edition  2012, 51, 1182-1186.  DOI: 10.1002/anie.201106985

  14. Absolute rate constants for 5-deazariboflavin triplet excited state in one-electron transfer processes


    15. Barra, M.; VanVeller, B.; Verberne, C.
    Journal of Photochemistry and Photobiology A: Chemistry  2011, 225, 113-116.  DOI: 10.1016/j.jphotochem.2011.10.007

  15. An experimental and molecular dynamics investigation into the amphiphilic nature of sulforhodamine B


    16. Polat, B. E.; Lin, S.; Mendenhall, J. D.; VanVeller, B.; Langer, R.; Blankschtein, D.
    Journal of Physical Chemistry B  2011, 115, 1394-1402.  DOI: 10.1021/jp109866q
              - Cover Article, link

  16. Synthesis of azaperylene-9,10-dicarboximides


    17. Andrew, T. L.; VanVeller, B.; Swager, T. M.
    Synlett  2010, 3045-3048.  DOI: 10.1055/s-0030-1259060

  17. Biocompatible post-polymerization functionalization of a water soluble poly(p-phenylene ethynylene)


    18. VanVeller, B.; Swager, T. M.
    Chemical Communications  2010, 5761–5763.  DOI: 10.1039/c0cc01456g

  18. Poly(aryleneethynylene)s


    19. VanVeller, B.; Swager, T. M.
    Design and Synthesis of Conjugated Polymers, Leclerc, M.; Morin, J., Eds. Wiley-VCH: Weinheim, 2010; Chapter 5
    DOI: 10.1002/9783527629787

  19. Rigid hydrophilic structures for improved properties of conjugated polymers and nitrotyrosine sensing in water


    20. VanVeller, B.; Miki, K.; Swager, T. M.
    Organic Letters  2010, 12, 1292–1295.  DOI: 10.1021/ol1001768

PATENTS    

  1. (S)-5-Ethynyl-anabasine, derivatives thereof, and related compositions and methods of making and using


    2. Zheng, F.; Du, X.; Robertson, A. P.; Yu, E. W.; VanVeller, B.; Martin, R. J.
    U.S. Provisional Patent No. 62/424,496.

  2. Protecting groups for boronic acids


    3. Raines, R. T.; VanVeller, B.; Aronoff, M. A.
    U.S. Patent No. 9,085,590.